Understanding a concept means you get it. Your understanding might be that your mother will always drive you to school if you miss the bus. Understanding implies abilities and dispositions with respect to an object.
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Comprehension usually used with of. The meaning of understanding is a mental grasp : Understanding is a relation between the knower and an object of understanding.
He noted bond's apparent lack of.
Knowledge about a subject, situation, etc. Or about how something works: How to use understanding in a sentence. Both comprehension and understanding can be used to talk about someone's ability to understand something.