Knowledge about a subject, situation, etc. Understanding implies abilities and dispositions with respect to an object. Or about how something works:
Pope Francis stresses cooperation, service, and Holy Spirit guidance in
He noted bond's apparent lack of. Understanding a concept means you get it. Understanding is a relation between the knower and an object of understanding.
Your understanding might be that your mother will always drive you to school if you miss the bus.
Both comprehension and understanding can be used to talk about someone's ability to understand something. Comprehension usually used with of. The meaning of understanding is a mental grasp : How to use understanding in a sentence.