Understanding a concept means you get it. Both comprehension and understanding can be used to talk about someone's ability to understand something. Knowledge about a subject, situation, etc.
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The meaning of understanding is a mental grasp : He noted bond's apparent lack of. How to use understanding in a sentence.
Understanding implies abilities and dispositions with respect to an object.
Or about how something works: Understanding is a relation between the knower and an object of understanding. Your understanding might be that your mother will always drive you to school if you miss the bus. Comprehension usually used with of.