Usually singular] the difference in their ages is about six months. The degree to which one person or thing differs from another: The difference between two things is the way in which they are unlike each other.
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The way in which two or more things which you are comparing are not the same: These nouns refer to a lack of correspondence or agreement. How to use difference in a sentence.
Difference is the most general:
Differences in color and size; The meaning of difference is the quality or state of being dissimilar or different.